The one rule for Thanksgiving Day games si that at least one home team covers. This will happen. The home field advantage, short rest advantage, no travel advantage is so large that it is completely unfair for the visiting squads who should get a bye week ebfore the game. Either a bye or the home team cannot have a home game the week before (both home teams had home games lst week).
LIONS +3.5 over Packers - The Lions are frauds, but I can see the Lions pulling out a win in shootout.
COWBOYS -14 over Jets - The Cowboys will wear really ugly jerseys, but the Jets defense is overmatched and their offense will not put many points up.
FALCONS +12.5 over Colts - The Colts injured list is just too long, and this could be another 20-13 game. Manning does need some decent WRs and linemen.
I'm going with all 3 home teams. Just a hunch.